ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2026
Target Type SINGLE PROTEIN
Preferred Name Beta-lactamase AmpC
Synonyms Beta-lactamase | Cephalosporinase | ampA | ampC
Organism Escherichia coli K-12
Species Group No
Protein Target Classification
  • enzyme > hydrolase

Target Components

Component Description Relationship Accession
Beta-lactamase SINGLE PROTEIN P00811

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0030288 (outer membrane-bounded periplasmic space)
GO:0042597 (periplasmic space)
GO Molecular Function GO:0008800 (beta-lactamase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0017001 (antibiotic catabolic process)
GO:0046677 (response to antibiotic)

Target Cross References - Protein

canSAR P00811
IntAct P00811
UniProt P00811 Q2M6F2

Target Cross References - Domain

InterPro IPR001466 (Beta-lactam-related.)
IPR001586 (Beta-lactam_class-C_AS.)
IPR012338 (Beta-lactam/transpept-like.)
Pfam PF00144 (Beta-lactamase)

Target Cross References - Structure

PDBe 1C3B 1FCM 1FCN 1FCO 1FSW 1FSY 1GA9 1I5Q 1IEL 1IEM 1KDS 1KDW 1KE0 1KE3 1KE4 1KVL 1KVM 1L0D 1L0E 1L0F 1L0G 1L2S 1LL5 1LL9 More...
CREDO 1C3B 1FCM 1FCN 1FCO 1FSW 1FSY 1GA9 1I5Q 1IEL 1IEM 1KDS 1KDW 1KE0 1KE3 1KE4 1KVL 1KVM 1L0D 1L0E 1L0F 1L0G 1L2S 1LL5 1LL9 More...
spacer
spacer