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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1907607
Target Type PROTEIN COMPLEX GROUP
Preferred Name GABA-A receptor; anion channel
Synonyms GABA theta subunit | GABA(A) receptor subunit alpha-1 | GABA(A) receptor subunit alpha-2 | GABA(A) receptor subunit alpha-3 | GABA(A) receptor subunit alpha-4 | GABA(A) receptor subunit alpha-5 | GABA(A) receptor subunit alpha-6 | GABA(A) receptor subunit beta-1 | GABA(A) receptor subunit beta-2 | GABA(A) receptor subunit beta-3 | GABA(A) receptor subunit delta | GABA(A) receptor subunit epsilon | GABA(A) receptor subunit gamma-1 | GABA(A) receptor subunit gamma-2 | GABA(A) receptor subunit gamma-3 | GABA(A) receptor subunit pi | Gabra-1 | Gabra-2 | Gabra-3 | Gabra-5 | Gabra-6 | Gabra1 | Gabra2 | Gabra3 | Gabra4 | Gabra5 | Gabra6 | Gabrb-1 | Gabrb-2 | Gabrb-3 | Gabrb1 | Gabrb2 | Gabrb3 | Gabrd | Gabre | Gabrg1 | Gabrg2 | Gabrg3 | Gabrp | Gabrq | Gamma-aminobutyric acid receptor subunit alpha-1 | Gamma-aminobutyric acid receptor subunit alpha-2 | Gamma-aminobutyric acid receptor subunit alpha-3 | Gamma-aminobutyric acid receptor subunit alpha-4 | Gamma-aminobutyric acid receptor subunit alpha-5 | Gamma-aminobutyric acid receptor subunit alpha-6 | Gamma-aminobutyric acid receptor subunit beta-1 | Gamma-aminobutyric acid receptor subunit beta-2 | Gamma-aminobutyric acid receptor subunit beta-3 | Gamma-aminobutyric acid receptor subunit delta | Gamma-aminobutyric acid receptor subunit epsilon | Gamma-aminobutyric acid receptor subunit gamma-1 | Gamma-aminobutyric acid receptor subunit gamma-2 | Gamma-aminobutyric acid receptor subunit gamma-3 | Gamma-aminobutyric acid receptor subunit pi
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > gaba-a receptor

Target Components

Component Description Relationship Accession
Gamma-aminobutyric acid receptor subunit delta GROUP MEMBER P18506
Gamma-aminobutyric acid receptor subunit epsilon GROUP MEMBER Q9ES14
Gamma-aminobutyric acid receptor subunit beta-2 GROUP MEMBER P63138
Gamma-aminobutyric acid receptor subunit alpha-2 GROUP MEMBER P23576
Gamma-aminobutyric acid receptor subunit alpha-5 GROUP MEMBER P19969
Gamma-aminobutyric acid receptor subunit alpha-3 GROUP MEMBER P20236
Gamma-aminobutyric acid receptor subunit alpha-1 GROUP MEMBER P62813
Gamma-aminobutyric acid receptor subunit gamma-2 GROUP MEMBER P18508
GABA theta subunit GROUP MEMBER Q91ZM7
Gamma-aminobutyric acid receptor subunit alpha-6 GROUP MEMBER P30191
Gamma-aminobutyric acid receptor subunit pi GROUP MEMBER O09028
Gamma-aminobutyric acid receptor subunit beta-3 GROUP MEMBER P63079
Gamma-aminobutyric acid receptor subunit beta-1 GROUP MEMBER P15431
Gamma-aminobutyric acid receptor subunit gamma-1 GROUP MEMBER P23574
Gamma-aminobutyric acid receptor subunit alpha-4 GROUP MEMBER P28471
Gamma-aminobutyric acid receptor subunit gamma-3 GROUP MEMBER P28473

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111365 GABA A receptor alpha-6/beta-2/gamma-2 PROTEIN COMPLEX
CHEMBL296 GABA receptor gamma-1 subunit SINGLE PROTEIN
CHEMBL2096683 Benzodiazepine receptors; peripheral & central SELECTIVITY GROUP
CHEMBL293 GABA receptor alpha-6 subunit SINGLE PROTEIN
CHEMBL341 GABA receptor alpha-2 subunit SINGLE PROTEIN
CHEMBL2111374 GABA A receptor alpha-5/beta-3/gamma-2 PROTEIN COMPLEX
CHEMBL3883322 Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/beta-3/gamma-2 PROTEIN COMPLEX
CHEMBL292 GABA receptor alpha-4 subunit SINGLE PROTEIN
CHEMBL2095167 GABA-A receptor; alpha-1/beta-2/gamma-2 PROTEIN COMPLEX
CHEMBL2111343 GABA A receptor alpha-3/beta-2/gamma-2 PROTEIN COMPLEX
CHEMBL328 GABA receptor alpha-3 subunit SINGLE PROTEIN
CHEMBL300 GABA receptor alpha-5 subunit SINGLE PROTEIN
CHEMBL343 GABA receptor alpha-1 subunit SINGLE PROTEIN
CHEMBL2111327 GABA A receptor alpha-2/beta-2/gamma-2 PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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