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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1901
Preferred Name Cholecystokinin A receptor
Synonyms CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKRA | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > cholecystokinin receptor

Target Components

Component Description Relationship Accession
Cholecystokinin receptor type A SINGLE PROTEIN P32238

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095185 Cholecystokinin receptor PROTEIN FAMILY

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL1200755 CERULETIDE DIETHYLAMINE Cholecystokinin A receptor agonist 4 PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000163394
Ensembl ENSG00000163394
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004951 (cholecystokinin receptor activity)
GO:0017046 (peptide hormone binding)
GO:0042277 (peptide binding)
GO Biological Process GO:0001764 (neuron migration)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007200 (phospholipase C-activating G-protein coupled receptor signaling pathway)
GO:0007409 (axonogenesis)
GO:0030900 (forebrain development)
GO:0032870 (cellular response to hormone stimulus)
GO:0038188 (cholecystokinin signaling pathway)
GO:0046883 (regulation of hormone secretion)
GO:1901652 (response to peptide)
Wikipedia Cholecystokinin_A_receptor

Target Cross References - Protein

canSAR P32238
Human Protein Atlas ENSG00000163394
IntAct P32238
Guide to Pharmacology 76
Open Targets ENSG00000163394
PharmGKB PA26142
Pharos P32238 (Tclin)
Reactome R-HSA-375276 (Peptide ligand-binding receptors.)
R-HSA-416476 (G alpha (q) signalling events.)
UniProt B2R9Z5 P32238

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000596 (Cholcy_rcpt_A.)
IPR009126 (Cholcskin_rcpt.)
IPR015276 (CholecystokininA_recpt_N.)
IPR017452 (GPCR_Rhodpsn_7TM.)
IPR036472 (CholecystokininA_recpt_N_sf.)
Pfam PF00001 (7tm_1)
PF09193 (CholecysA-Rec_N)