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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1744528
Target Type SINGLE PROTEIN
Preferred Name 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Synonyms 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase | 3-beta hydroxysterol dehydrogenase | 3-beta-HSD | 3-beta-hydroxy-5-ene steroid dehydrogenase | 3-beta-hydroxy-Delta(5)-steroid dehydrogenase | 3BHSD | Cholesterol dehydrogenase | Delta-5-3-ketosteroid isomerase | Progesterone reductase | Steroid Delta-isomerase
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase SINGLE PROTEIN P9WQP7

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0003854 (3-beta-hydroxy-delta5-steroid dehydrogenase activity)
GO:0004769 (steroid delta-isomerase activity)
GO:0016491 (oxidoreductase activity)
GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
GO:0016853 (isomerase activity)
GO:0070403 (NAD+ binding)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006694 (steroid biosynthetic process)
GO:0008152 (metabolic process)
GO:0008202 (steroid metabolic process)
GO:0016042 (lipid catabolic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

UniProt L0T7C3 O53454 P9WQP7 Q7D8U6

Target Cross References - Domain

InterPro IPR002225 (3Beta_OHSteriod_DH/Estase.)
IPR016040 (NAD(P)-bd_dom.)
Pfam PF01073 (3Beta_HSD)
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