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Target Report Card

Target Name and Classification

Target ID CHEMBL1743124
Preferred Name Solute carrier organic anion transporter family member 2B1
Synonyms KIAA0880 | OATP-B | OATP-RP2 | OATP2B1 | OATPB | OATPRP2 | Organic anion transporter B | Organic anion transporter polypeptide-related protein 2 | SLC21A9 | SLCO2B1 | Solute carrier family 21 member 9 | Solute carrier organic anion transporter family member 2B1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc21/slco family of organic anion transporting polypeptides

Target Components

Component Description Relationship Accession
Solute carrier organic anion transporter family member 2B1 SINGLE PROTEIN O94956

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000137491
Ensembl ENSG00000137491
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0005215 (transporter activity)
GO:0008514 (organic anion transmembrane transporter activity)
GO:0015125 (bile acid transmembrane transporter activity)
GO:0015347 (sodium-independent organic anion transmembrane transporter activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0015721 (bile acid and bile salt transport)
GO:0043252 (sodium-independent organic anion transport)
Wikipedia SLCO2B1

Target Cross References - Protein

Human Protein Atlas ENSG00000137491
Guide to Pharmacology 1224
Open Targets ENSG00000137491
PharmGKB PA35845
Reactome R-HSA-879518 (Transport of organic anions.)
UniProt A8K2G9 B4DGA9 B4DTB0 E7ERN5 E9PPU8 O94956 Q9H2Z0 Q9UFU1

Target Cross References - Domain

InterPro IPR002350 (Kazal_dom.)
IPR004156 (OA_transporter.)
IPR020846 (MFS_dom.)
Pfam PF03137 (OATP)