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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1671610
Target Type SINGLE PROTEIN
Preferred Name Cytosol aminopeptidase
Synonyms Cytosol aminopeptidase | LAP-3 | LAP3 | Leucine aminopeptidase 3 | Leucyl aminopeptidase | Peptidase S | Proline aminopeptidase | Prolyl aminopeptidase
Organism Bos taurus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Cytosol aminopeptidase SINGLE PROTEIN P00727

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005622 (intracellular)
GO:0005634 (nucleus)
GO:0005654 (nucleoplasm)
GO:0005737 (cytoplasm)
GO:0005739 (mitochondrion)
GO:0005925 (focal adhesion)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008235 (metalloexopeptidase activity)
GO:0016787 (hydrolase activity)
GO:0030145 (manganese ion binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0019538 (protein metabolic process)

Target Cross References - Protein

canSAR P00727
UniProt P00727 Q2HJH5 Q2PC24

Target Cross References - Domain

InterPro IPR000819 (Peptidase_M17_C.)
IPR008283 (Peptidase_M17_N.)
IPR011356 (Leucine_aapep/pepB.)
IPR023042 (Peptidase_M17_leu_NH2_pept.)
Pfam PF00883 (Peptidase_M17)
PF02789 (Peptidase_M17_N)

Target Cross References - Structure

PDBe 1BLL 1BPM 1BPN 1LAM 1LAN 1LAP 1LCP 2EWB 2J9A
CREDO 1BLL 1BPM 1BPN 1LAM 1LAN 1LAP 1LCP 2EWB 2J9A
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