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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1287620
Target Type SINGLE PROTEIN
Preferred Name Fructose-bisphosphate aldolase
Synonyms FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-bisphosphate aldolase | fba
Organism Mycobacterium tuberculosis
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Fructose-bisphosphate aldolase SINGLE PROTEIN P9WQA3

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO:0005618 (cell wall)
GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0004332 (fructose-bisphosphate aldolase activity)
GO:0008270 (zinc ion binding)
GO:0016829 (lyase activity)
GO:0016832 (aldehyde-lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0006094 (gluconeogenesis)
GO:0006096 (glycolytic process)

Target Cross References - Protein

UniProt L0T684 O06313 P67475 P9WQA3

Target Cross References - Domain

InterPro IPR000771 (Ketose_bisP_aldolase_II.)
IPR006411 (Fruct_bisP_bact.)
IPR013785 (Aldolase_TIM.)
Pfam PF01116 (F_bP_aldolase)

Target Cross References - Structure

PDBe 3EKL 3EKZ 3ELF 4A21 4A22 4DEF 4DEL 4LV4
CREDO 3EKL 3EKZ 3ELF 4A21 4A22 4DEF 4DEL 4LV4
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