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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1287603
Target Type SINGLE PROTEIN
Preferred Name DNA gyrase subunit B
Synonyms DNA gyrase subunit B | gyrB
Organism Escherichia coli
Species Group No
Protein Target Classification
  • enzyme > isomerase

Target Components

Component Description Relationship Accession
DNA gyrase subunit B SINGLE PROTEIN C3SLN2

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3885561 DNA gyrase subunit A/subunit B PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005694 (chromosome)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003677 (DNA binding)
GO:0003916 (DNA topoisomerase activity)
GO:0003918 (DNA topoisomerase type II (ATP-hydrolyzing) activity)
GO:0005524 (ATP binding)
GO:0016853 (isomerase activity)
GO:0046872 (metal ion binding)
GO:0061505 (DNA topoisomerase II activity)
GO Biological Process GO:0006261 (DNA-dependent DNA replication)
GO:0006265 (DNA topological change)

Target Cross References - Protein

UniProt C3SLN2

Target Cross References - Domain

InterPro IPR001241 (Topo_IIA.)
IPR002288 (DNA_gyrase_B_C.)
IPR003594 (HATPase_C.)
IPR006171 (TOPRIM_domain.)
IPR011557 (GyrB.)
IPR013506 (Topo_IIA_bsu_dom2.)
IPR013759 (Topo_IIA_B_C.)
IPR013760 (Topo_IIA-like_dom_sf.)
IPR014721 (Ribosomal_S5_D2-typ_fold_subgr.)
IPR018522 (TopoIIA_CS.)
IPR020568 (Ribosomal_S5_D2-typ_fold.)
IPR034160 (TOPRIM_GyrB.)
IPR036890 (HATPase_C_sf.)
Pfam PF00204 (DNA_gyraseB)
PF00986 (DNA_gyraseB_C)
PF01751 (Toprim)
PF02518 (HATPase_c)
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