ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL1169597
Target Type SINGLE PROTEIN
Preferred Name 6-phosphogluconate dehydrogenase, decarboxylating
Synonyms 6-phosphogluconate dehydrogenase, decarboxylating | PGD
Organism Ovis aries
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
6-phosphogluconate dehydrogenase, decarboxylating SINGLE PROTEIN P00349

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004616 (phosphogluconate dehydrogenase (decarboxylating) activity)
GO:0016491 (oxidoreductase activity)
GO Biological Process GO:0006098 (pentose-phosphate shunt)
GO:0019521 (D-gluconate metabolic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P00349
UniProt P00349

Target Cross References - Domain

InterPro IPR006113 (6PGDH_Gnd/GntZ.)
IPR006114 (6PGDH_C.)
IPR006115 (6PGDH_NADP-bd.)
IPR006183 (Pgluconate_DH.)
IPR006184 (6PGdom_BS.)
IPR008927 (6-PGluconate_DH_C-like.)
IPR012284 (6PGD_dom_3.)
IPR013328 (6PGD_dom_2.)
IPR016040 (NAD(P)-bd_dom.)
Pfam PF00393 (6PGD)
PF03446 (NAD_binding_2)

Target Cross References - Structure

PDBe 1PGN 1PGO 1PGP 1PGQ 2PGD
CREDO 1PGN 1PGO 1PGP 1PGQ 2PGD
spacer
spacer