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Target Report Card

Target Name and Classification

Target ID CHEMBL1075167
Preferred Name Homeodomain-interacting protein kinase 4
Synonyms HIPK4 | Homeodomain-interacting protein kinase 4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > cmgc protein kinase group > cmgc protein kinase dyrk family > cmgc protein kinase hipk subfamily

Target Components

Component Description Relationship Accession
Homeodomain-interacting protein kinase 4 SINGLE PROTEIN Q8NE63

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000160396
Ensembl ENSG00000160396
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0016572 (histone phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0046777 (protein autophosphorylation)
GO:1901796 (regulation of signal transduction by p53 class mediator)

Target Cross References - Protein

canSAR Q8NE63
Human Protein Atlas ENSG00000160396
IntAct Q8NE63
Guide to Pharmacology 2036
Open Targets ENSG00000160396
PharmGKB PA134883524
Pharos Q8NE63 (Tchem)
UniProt A8K863 Q8NE63 Q96M54

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)