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Target Report Card

Target Name and Classification

Target ID CHEMBL1075155
Preferred Name Serine/threonine-protein kinase 38
Synonyms NDR1 protein kinase | Nuclear Dbf2-related kinase 1 | STK38 | Serine/threonine-protein kinase 38 | Synonyms=NDR1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > agc protein kinase group > agc protein kinase ndr family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase 38 SINGLE PROTEIN Q15208

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000112079
Ensembl ENSG00000112079
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0000287 (magnesium ion binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0031435 (mitogen-activated protein kinase kinase kinase binding)
GO:0045296 (cadherin binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006464 (cellular protein modification process)
GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0035556 (intracellular signal transduction)
GO:0043407 (negative regulation of MAP kinase activity)
Wikipedia STK38

Target Cross References - Protein

canSAR Q15208
Human Protein Atlas ENSG00000112079
IntAct Q15208
Guide to Pharmacology 1517
Open Targets ENSG00000112079
PharmGKB PA38251
Pharos Q15208 (Tbio)
UniProt Q15208 Q503A1

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR000961 (AGC-kinase_C.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017892 (Pkinase_C.)
Pfam PF00069 (Pkinase)
PF00433 (Pkinase_C)