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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6196
Preferred Name UDP-glucuronosyltransferase 2B4
Synonyms HLUG25 | Hyodeoxycholic acid-specific UDPGT | UDP-glucuronosyltransferase 2B4 | UDPGT 2B4 | UDPGTh-1 | UGT2B11 | UGT2B4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
UDP-glucuronosyltransferase 2B4 SINGLE PROTEIN P06133

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000156096
Ensembl ENSG00000156096
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031090 (organelle membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0001972 (retinoic acid binding)
GO:0015020 (glucuronosyltransferase activity)
GO:0016740 (transferase activity)
GO:0016757 (transferase activity, transferring glycosyl groups)
GO:0016758 (transferase activity, transferring hexosyl groups)
GO Biological Process GO:0006711 (estrogen catabolic process)
GO:0006805 (xenobiotic metabolic process)
GO:0008152 (metabolic process)
GO:0009813 (flavonoid biosynthetic process)
GO:0052695 (cellular glucuronidation)
GO:0052696 (flavonoid glucuronidation)
Wikipedia UGT2B4

Target Cross References - Protein

canSAR P06133
Human Protein Atlas ENSG00000156096
IntAct P06133
Open Targets ENSG00000156096
PharmGKB PA360
Reactome R-HSA-156588 (Glucuronidation.)
UniProt A6NCP7 B4DT75 G5E9X8 O60731 O60867 O75614 P06133 P36538 Q1HBF9 Q6QQX7

Target Cross References - Domain

InterPro IPR002213 (UDP_glucos_trans.)
Pfam PF00201 (UDPGT)