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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6120
Target Type SINGLE PROTEIN
Preferred Name Solute carrier family 22 member 12
Synonyms Object
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc22 family of organic cation and anion transporters

Target Components

Component Description Relationship Accession
Solute carrier family 22 member 12 SINGLE PROTEIN Q96S37

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000197891
Ensembl ENSG00000197891
GO Cellular Component GO:0005887 (integral component of plasma membrane)
GO:0016324 (apical plasma membrane)
GO:0070062 (extracellular exosome)
GO:0016021 (integral component of membrane)
GO:0031526 (brush border membrane)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0030165 (PDZ domain binding)
GO:0015143 (urate transmembrane transporter activity)
GO:0005452 (inorganic anion exchanger activity)
GO:0015347 (sodium-independent organic anion transmembrane transporter activity)
GO Biological Process GO:0015747 (urate transport)
GO:1903825 (organic acid transmembrane transport)
GO:0042493 (response to drug)
GO:0046415 (urate metabolic process)
GO:0055085 (transmembrane transport)
GO:0098656 (anion transmembrane transport)
GO:0043252 (sodium-independent organic anion transport)
GO:0019725 (cellular homeostasis)
Wikipedia SLC22A12

Target Cross References - Protein

canSAR Q96S37
CGD Hypouricemia, renal 1
Human Protein Atlas ENSG00000197891
IntAct Q96S37
Guide to Pharmacology 1031 (Urate anion exchanger 1)
PharmGKB PA38478
UniProt B7WPG1 Q96S37 Q19PF8 Q19PF9 Q19PG0 Q96DT2 Q6UXW3 Q19PF7

Target Cross References - Domain

InterPro IPR011701 (MFS.)
IPR020846 (MFS_dom.)
Pfam PF07690 (MFS_1)
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