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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6117
Target Type SINGLE PROTEIN
Preferred Name Tyrosine-protein phosphatase non-receptor type 9
Synonyms PTPN9 | PTPase MEG2 | Protein-tyrosine phosphatase MEG2 | Tyrosine-protein phosphatase non-receptor type 9
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Tyrosine-protein phosphatase non-receptor type 9 SINGLE PROTEIN P43378

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000169410
Ensembl ENSG00000169410
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004721 (phosphoprotein phosphatase activity)
GO:0004725 (protein tyrosine phosphatase activity)
GO:0004726 (non-membrane spanning protein tyrosine phosphatase activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0016791 (phosphatase activity)
GO Biological Process GO:0006470 (protein dephosphorylation)
GO:0016311 (dephosphorylation)
GO:0035335 (peptidyl-tyrosine dephosphorylation)
Wikipedia PTPN9

Target Cross References - Protein

canSAR P43378
Human Protein Atlas ENSG00000169410
IntAct P43378
Open Targets ENSG00000169410
PharmGKB PA34005
UniProt P43378 Q53XR9

Target Cross References - Domain

InterPro IPR000242 (PTPase_domain.)
IPR000387 (TYR_PHOSPHATASE_dom.)
IPR001251 (CRAL-TRIO_dom.)
IPR003595 (Tyr_Pase_cat.)
IPR011074 (CRAL/TRIO_N_dom.)
IPR016130 (Tyr_Pase_AS.)
IPR029021 (Prot-tyrosine_phosphatase-like.)
Pfam PF00102 (Y_phosphatase)
PF00650 (CRAL_TRIO)

Target Cross References - Structure

PDBe 2PA5 4GE2 4GE5 4GE6 4ICZ
CREDO 2PA5 4GE2 4GE5 4GE6 4ICZ
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