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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6103
Target Type SINGLE PROTEIN
Preferred Name Transcription factor Sp1
Synonyms SP1 | TSFP1 | Transcription factor Sp1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Transcription factor Sp1 SINGLE PROTEIN P08047

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000185591
Ensembl ENSG00000185591
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0003690 (double-stranded DNA binding)
GO:0003700 (sequence-specific DNA binding transcription factor activity)
GO:0003702 (RNA polymerase II transcription factor activity)
GO:0008022 (protein C-terminus binding)
GO:0008134 (transcription factor binding)
GO:0008270 (zinc ion binding)
GO:0010843 (promoter binding)
GO:0016563 (transcription activator activity)
GO:0042803 (protein homodimerization activity)
GO:0042826 (histone deacetylase binding)
GO:0043565 (sequence-specific DNA binding)
GO Biological Process GO:0043923 (positive regulation by host of viral transcription)
GO:0045817 (positive regulation of transcription from RNA polymerase II promoter, global)
Wikipedia Sp1_transcription_factor

Target Cross References - Protein

canSAR P08047
Human Protein Atlas ENSG00000185591
IntAct P08047
PharmGKB PA36042
UniProt P08047 Q86TN8 Q9H3Q5 Q9NR51 Q9NY21 Q9NYE7

Target Cross References - Domain

InterPro IPR007087 (Znf_C2H2.)
IPR013087 (Znf_C2H2/integrase_DNA-bd.)
IPR015880 (Znf_C2H2-like.)
Pfam PF00096 (zf-C2H2)
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