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Target Report Card

Target Name and Classification

Target ID CHEMBL6014
Preferred Name Testis-specific serine/threonine-protein kinase 2
Synonyms DGS-G | DGSG | DiGeorge syndrome protein G | SPOGA2 | STK22B | Serine/threonine-protein kinase 22B | TSK-2 | TSK2 | TSSK-2 | TSSK2 | Testis-specific kinase 2 | Testis-specific serine/threonine-protein kinase 2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase tssk family

Target Components

Component Description Relationship Accession
Testis-specific serine/threonine-protein kinase 2 SINGLE PROTEIN Q96PF2

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000206203
Ensembl ENSG00000206203
GO Cellular Component GO:0001669 (acrosomal vesicle)
GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005814 (centriole)
GO:0005856 (cytoskeleton)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0000287 (magnesium ion binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0007275 (multicellular organism development)
GO:0007283 (spermatogenesis)
GO:0007286 (spermatid development)
GO:0016310 (phosphorylation)
GO:0030154 (cell differentiation)
GO:0035556 (intracellular signal transduction)
GO:0046777 (protein autophosphorylation)
Wikipedia TSSK2

Target Cross References - Protein

canSAR Q96PF2
Human Protein Atlas ENSG00000206203
IntAct Q96PF2
Guide to Pharmacology 2258
Open Targets ENSG00000206203
PharmGKB PA36208
Pharos Q96PF2 (Tbio)
UniProt Q8IY55 Q96PF2

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)