ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5967
Target Type SINGLE PROTEIN
Preferred Name Kinesin-like protein KIF2C
Synonyms KIF2C | KNSL6 | Kinesin-like protein 6 | Kinesin-like protein KIF2C | MCAK | Mitotic centromere-associated kinesin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Kinesin-like protein KIF2C SINGLE PROTEIN Q99661

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000142945
Ensembl ENSG00000142945
GO Cellular Component GO:0000777 (condensed chromosome kinetochore)
GO:0005634 (nucleus)
GO:0005829 (cytosol)
GO:0005871 (kinesin complex)
GO:0005874 (microtubule)
GO Molecular Function GO:0003777 (microtubule motor activity)
GO:0005524 (ATP binding)
GO:0019237 (centromeric DNA binding)
GO:0051010 (microtubule plus-end binding)
GO Biological Process GO:0000236 (mitotic prometaphase)
GO:0007018 (microtubule-based movement)
GO:0007019 (microtubule depolymerization)
GO:0007059 (chromosome segregation)
GO:0007596 (blood coagulation)
GO:0008283 (cell proliferation)
GO:0030951 (establishment or maintenance of microtubule cytoskeleton polarity)
GO:0051301 (cell division)
GO:0051983 (regulation of chromosome segregation)
Wikipedia KIF2C

Target Cross References - Protein

canSAR Q99661
Human Protein Atlas ENSG00000142945
IntAct Q99661
PharmGKB PA30182
Reactome REACT_152 (Cell Cycle, Mitotic.)
REACT_383 (DNA Replication.)
REACT_604 (Hemostasis.)
UniProt B3ITR9 Q5JR88 Q6ICU1 Q96C18 Q96HB8 Q99661 Q9BWV8

Target Cross References - Domain

InterPro IPR001752 (Kinesin_motor_dom.)
IPR019821 (Kinesin_motor_CS.)
Pfam PF00225 (Kinesin)

Target Cross References - Structure

PDBe 2HEH
CREDO 2HEH
spacer
spacer