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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5920
Target Type SINGLE PROTEIN
Preferred Name N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Synonyms Mannose 6-phosphate-uncovering enzyme | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | NAGPA | Phosphodiester alpha-GlcNAcase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase SINGLE PROTEIN Q9UK23

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000103174
Ensembl ENSG00000103174
GO Cellular Component GO:0005794 (Golgi apparatus)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0032580 (Golgi cisterna membrane)
GO Molecular Function GO:0003944 (N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0006464 (cellular protein modification process)
GO:0006486 (protein glycosylation)
GO:0006622 (protein targeting to lysosome)
GO:0007040 (lysosome organization)
Wikipedia NAGPA

Target Cross References - Protein

canSAR Q9UK23
Human Protein Atlas ENSG00000103174
IntAct Q9UK23
Open Targets ENSG00000103174
PharmGKB PA134940049
UniProt B2RAS1 Q96EJ8 Q9UK23

Target Cross References - Domain

InterPro IPR000742 (EGF-like_dom.)
IPR013032 (EGF-like_CS.)
IPR018711 (NAGPA.)
Pfam PF09992 (NAGPA)
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