ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5891
Target Type SINGLE PROTEIN
Preferred Name Protein arginine N-methyltransferase 3
Synonyms HRMT1L3 | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 | PRMT3 | Protein arginine N-methyltransferase 3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • epigenetic regulator > writer > protein methyltransferase > protein arginine methyltransferase

Target Components

Component Description Relationship Accession
Protein arginine N-methyltransferase 3 SINGLE PROTEIN O60678

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000185238
Ensembl ENSG00000185238
GO Molecular Function GO:0008270 (zinc ion binding)
Wikipedia PRMT3

Target Cross References - Protein

Human Protein Atlas ENSG00000185238
IntAct O60678
Guide to Pharmacology 1254 (protein arginine methyltransferase 3)
PharmGKB PA29462
UniProt B4DUC7 O60678

Target Cross References - Domain

InterPro IPR007087 (Znf_C2H2.)
IPR010456 (Ribosomal-L11_MeTrfase_PrmA.)
IPR015880 (Znf_C2H2-like.)
Pfam PF06325 (PrmA)

Target Cross References - Structure

PDBe 2FYT
CREDO 2FYT
spacer
spacer