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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5877
Target Type SINGLE PROTEIN
Preferred Name Beta-hexosaminidase subunit beta
Synonyms Beta-N-acetylhexosaminidase subunit beta | Beta-hexosaminidase subunit beta | Beta-hexosaminidase subunit beta chain A | Beta-hexosaminidase subunit beta chain B | Cervical cancer proto-oncogene 7 protein | HCC-7 | HEXB | Hexosaminidase subunit B | N-acetyl-beta-glucosaminidase subunit beta
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Beta-hexosaminidase subunit beta SINGLE PROTEIN P07686

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3038485 Beta-N-acetyl-D-hexosaminidase-A/B PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000049860
Ensembl ENSG00000049860
GO Cellular Component GO:0005764 (lysosome)
GO Molecular Function GO:0042803 (protein homodimerization activity)
GO:0043169 (cation binding)
GO:0046982 (protein heterodimerization activity)
Wikipedia HEXB

Target Cross References - Protein

canSAR P07686
CGD Sandhoff disease
Human Protein Atlas ENSG00000049860
PharmGKB PA29257
UniProt P07686

Target Cross References - Domain

InterPro IPR001540 (Glyco_hydro_20.)
IPR013781 (Glyco_hydro_subgr_catalytic.)
IPR015882 (Acetylhexosaminidase_sua/b.)
IPR015883 (Glyco_hydro_20_cat-core.)
IPR017853 (Glycoside_hydrolase_SF.)
Pfam PF00728 (Glyco_hydro_20)
PF02838 (Glyco_hydro_20b)

Target Cross References - Structure

PDBe 1NOU 1NOW 1NP0 1O7A 2GJX 2GK1 3LMY
CREDO 1NOU 1NOW 1NP0 1O7A 2GJX 2GK1 3LMY
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