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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5850
Target Type SINGLE PROTEIN
Preferred Name Mas-related G-protein coupled receptor member X1
Synonyms MRGPRX1 | MRGX1 | Mas-related G-protein coupled receptor member X1 | SNSR3 | SNSR4 | Sensory neuron-specific G-protein coupled receptor 3/4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Mas-related G-protein coupled receptor member X1 SINGLE PROTEIN Q96LB2

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000170255
Ensembl ENSG00000170255
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO Biological Process GO:0006953 (acute-phase response)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
Wikipedia MRGPRX1

Target Cross References - Protein

canSAR Q96LB2
Human Protein Atlas ENSG00000170255
Guide to Pharmacology 156
Open Targets ENSG00000170255
PharmGKB PA142671334
Pharos Q96LB2 (Tbio)
UniProt Q4V9L2 Q8TDD8 Q8TDD9 Q96LB2

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR017452 (GPCR_Rhodpsn_7TM.)
IPR026234 (MRGPCRFAMILY.)
IPR027338 (MRGPCRX1.)
Pfam PF00001 (7tm_1)
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