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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5842
Target Type SINGLE PROTEIN
Preferred Name Low affinity immunoglobulin gamma Fc region receptor III-B
Synonyms CD16B | CD_antigen=CD16b | FCG3 | FCGR3 | FCGR3B | Fc-gamma RIII | Fc-gamma RIII-beta | Fc-gamma RIIIb | FcR-10 | FcRIII | FcRIIIb | IGFR3 | IgG Fc receptor III-1 | Low affinity immunoglobulin gamma Fc region receptor III-B
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Low affinity immunoglobulin gamma Fc region receptor III-B SINGLE PROTEIN O75015

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000162747
Ensembl ENSG00000162747
GO Cellular Component GO:0005576 (extracellular region)
GO:0005886 (plasma membrane)
GO:0031225 (anchored to membrane)
GO Molecular Function GO:0004872 (receptor activity)
GO:0019864 (IgG binding)
GO Biological Process GO:0006955 (immune response)
Wikipedia FCGR3B

Target Cross References - Protein

canSAR O75015
Human Protein Atlas ENSG00000162747
IntAct O75015
PharmGKB PA28066
UniProt O75015

Target Cross References - Domain

InterPro IPR003599 (Ig_sub.)
IPR007110 (Ig-like.)
IPR013783 (Ig-like_fold.)

Target Cross References - Structure

PDBe 1E4J 1E4K 1FNL 1T83 1T89
CREDO 1E4J 1E4K 1FNL 1T83 1T89
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