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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5792
Target Type SINGLE PROTEIN
Preferred Name Cytochrome P450 3A43
Synonyms CYP3A43 | Cytochrome P450 3A43
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Cytochrome P450 3A43 SINGLE PROTEIN Q9HB55

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2364675 Cytochrome P450 3A PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000021461
Ensembl ENSG00000021461
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0031090 (organelle membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0004497 (monooxygenase activity)
GO:0005506 (iron ion binding)
GO:0016491 (oxidoreductase activity)
GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
GO:0016712 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen)
GO:0020037 (heme binding)
GO:0046872 (metal ion binding)
GO:0070330 (aromatase activity)
GO Biological Process GO:0055114 (oxidation-reduction process)
Wikipedia CYP3A43

Target Cross References - Protein

canSAR Q9HB55
Human Protein Atlas ENSG00000021461
Open Targets ENSG00000021461
PharmGKB PA427
Reactome R-HSA-211958 (Miscellaneous substrates.)
R-HSA-211981 (Xenobiotics.)
UniProt Q495Y1 Q75MK2 Q75MK3 Q9HB52 Q9HB53 Q9HB54 Q9HB55 Q9HB57

Target Cross References - Domain

InterPro IPR001128 (Cyt_P450.)
IPR002402 (Cyt_P450_E_grp-II.)
IPR008072 (Cyt_P450_E_CYP3A.)
IPR017972 (Cyt_P450_CS.)
Pfam PF00067 (p450)
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