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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5784
Target Type SINGLE PROTEIN
Preferred Name NUAK family SNF1-like kinase 1
Synonyms AMPK-related protein kinase 5 | ARK5 | ARK5 | KIAA0537 | NUAK family SNF1-like kinase 1 | NUAK1 | OMPHK1 | Omphalocele kinase 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase camk1 family > camk protein kinase nuak subfamily

Target Components

Component Description Relationship Accession
NUAK family SNF1-like kinase 1 SINGLE PROTEIN O60285

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000074590
Ensembl ENSG00000074590
GO Molecular Function GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
Wikipedia NUAK1

Target Cross References - Protein

canSAR O60285
Human Protein Atlas ENSG00000074590
IntAct O60285
Guide to Pharmacology 2129 (NUAK family, SNF1-like kinase, 1)
PharmGKB PA142671242
UniProt A7MD39 O60285 Q96KA8

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_cat_dom.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR008271 (Ser/Thr_prot_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
Pfam PF00069 (Pkinase)
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