ChEMBL logo


ChEMBL Statistics
  Loading Statistics...

Target Report Card

Target Name and Classification

Target ID CHEMBL5762
Preferred Name Sodium- and chloride-dependent taurine transporter
Synonyms SLC6A6 | Sodium- and chloride-dependent taurine transporter | Solute carrier family 6 member 6
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc06 neurotransmitter transporter family

Target Components

Component Description Relationship Accession
Sodium- and chloride-dependent taurine transporter SINGLE PROTEIN P31641

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000131389
Ensembl ENSG00000131389
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0005328 (neurotransmitter:sodium symporter activity)
GO:0005369 (taurine:sodium symporter activity)
GO:0015171 (amino acid transmembrane transporter activity)
GO Biological Process GO:0006520 (cellular amino acid metabolic process)
Wikipedia SLC6A6

Target Cross References - Protein

canSAR P31641
Human Protein Atlas ENSG00000131389
Guide to Pharmacology 933 (TauT)
PharmGKB PA35912
Reactome REACT_13 (Metabolism of amino acids and derivatives.)
REACT_15518 (Transmembrane transport of small molecules.)
REACT_19419 (Amino acid and oligopeptide SLC transporters.)
REACT_20679 (Amine compound SLC transporters.)
UniProt P31641 Q9BXB0

Target Cross References - Domain

InterPro IPR000175 (Na/ntran_symport.)
IPR002434 (Na/ntran_symport_taurine.)
Pfam PF00209 (SNF)