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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5762
Preferred Name Sodium- and chloride-dependent taurine transporter
Synonyms SLC6A6 | Sodium- and chloride-dependent taurine transporter | Solute carrier family 6 member 6
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc06 neurotransmitter transporter family

Target Components

Component Description Relationship Accession
Sodium- and chloride-dependent taurine transporter SINGLE PROTEIN P31641

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000131389
Ensembl ENSG00000131389
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0005328 (neurotransmitter:sodium symporter activity)
GO:0005369 (taurine:sodium symporter activity)
GO:0015171 (amino acid transmembrane transporter activity)
GO:0015293 (symporter activity)
GO Biological Process GO:0003333 (amino acid transmembrane transport)
GO:0006520 (cellular amino acid metabolic process)
GO:0006810 (transport)
GO:0006836 (neurotransmitter transport)
GO:0006865 (amino acid transport)
GO:0015734 (taurine transport)
Wikipedia SLC6A6

Target Cross References - Protein

canSAR P31641
Human Protein Atlas ENSG00000131389
IntAct P31641
Open Targets ENSG00000131389
PharmGKB PA35912
Reactome R-HSA-352230 (Amino acid transport across the plasma membrane.)
R-HSA-442660 (Na+/Cl- dependent neurotransmitter transporters.)
UniProt B2RNU7 P31641 Q9BRI2 Q9BXB0

Target Cross References - Domain

InterPro IPR000175 (Na/ntran_symport.)
IPR002434 (Na/ntran_symport_taurine.)
Pfam PF00209 (SNF)