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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5737
Target Type SINGLE PROTEIN
Preferred Name VIP peptides
Synonyms Intestinal peptide PHM-27 | Intestinal peptide PHV-42 | Peptide histidine methioninamide 27 | Peptide histidine valine 42 | VIP peptides | VIP | VIP | Vasoactive intestinal peptide | Vasoactive intestinal polypeptide
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
VIP peptides SINGLE PROTEIN P01282

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000146469
Ensembl ENSG00000146469
GO Cellular Component GO:0005576 (extracellular region)
GO:0043025 (neuronal cell body)
GO Molecular Function GO:0005102 (receptor binding)
GO:0005179 (hormone activity)
GO:0005184 (neuropeptide hormone activity)
GO:0005515 (protein binding)
GO Biological Process GO:0001878 (response to yeast)
GO:0001938 (positive regulation of endothelial cell proliferation)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007589 (body fluid secretion)
GO:0007611 (learning or memory)
GO:0008284 (positive regulation of cell proliferation)
GO:0010579 (positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway)
GO:0019731 (antibacterial humoral response)
GO:0019732 (antifungal humoral response)
GO:0032880 (regulation of protein localization)
GO:0043066 (negative regulation of apoptotic process)
GO:0043267 (negative regulation of potassium ion transport)
GO:0045087 (innate immune response)
GO:0045732 (positive regulation of protein catabolic process)
GO:0045909 (positive regulation of vasodilation)
GO:0048255 (mRNA stabilization)
GO:0048662 (negative regulation of smooth muscle cell proliferation)
GO:0050829 (defense response to Gram-negative bacterium)
GO:0050830 (defense response to Gram-positive bacterium)
GO:0051930 (regulation of sensory perception of pain)
GO:0060406 (positive regulation of penile erection)
GO:0070459 (prolactin secretion)
Wikipedia Vasoactive_intestinal_peptide

Target Cross References - Protein

canSAR P01282
Human Protein Atlas ENSG00000146469
IntAct P01282
Open Targets ENSG00000146469
PharmGKB PA37312
Reactome R-HSA-418555 (G alpha (s) signalling events.)
UniProt P01282 Q5TCY8 Q5TCY9 Q96QK3

Target Cross References - Domain

InterPro IPR000532 (Glucagon_GIP_secretin_VIP.)
IPR015523 (VIP.)
Pfam PF00123 (Hormone_2)
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