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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5736
Target Type SINGLE PROTEIN
Preferred Name Glucagon
Synonyms GCG | GLP-1 | GLP-1(7-36) | GLP-1(7-37) | GLP-2 | GRPP | Glicentin | Glicentin-related polypeptide | Glucagon | Glucagon-like peptide 1 | Glucagon-like peptide 1(7-36) | Glucagon-like peptide 1(7-37) | Glucagon-like peptide 2 | Incretin hormone | OXM | OXY | Oxyntomodulin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Glucagon SINGLE PROTEIN P01275

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000115263
Ensembl ENSG00000115263
GO Cellular Component GO:0005625 (soluble fraction)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0005179 (hormone activity)
GO Biological Process GO:0006112 (energy reserve metabolic process)
GO:0007631 (feeding behavior)
GO:0008283 (cell proliferation)
GO:0050796 (regulation of insulin secretion)
GO:0071377 (cellular response to glucagon stimulus)
Wikipedia Glucagon

Target Cross References - Protein

canSAR P01275
Human Protein Atlas ENSG00000115263
PharmGKB PA28606
Reactome REACT_14797 (Signaling by GPCR.)
REACT_1505 (Integration of energy metabolism.)
REACT_15380 (Diabetes pathways.)
UniProt A6NN65 P01275 Q53TP6

Target Cross References - Domain

InterPro IPR000532 (Glucagon_GIP_secretin_VIP.)
IPR015550 (Glucagon-like.)
Pfam PF00123 (Hormone_2)

Target Cross References - Structure

PDBe 1BH0 2G49 3IOL
CREDO 1BH0 2G49 3IOL
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