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Target Report Card

Target Name and Classification

Target ID CHEMBL5652
Target Type SINGLE PROTEIN
Preferred Name Glucose-dependent insulinotropic receptor
Synonyms G-protein coupled receptor 119 | GPR119 | Glucose-dependent insulinotropic receptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > lipid-like ligand receptor (family a gpcr)

Target Components

Component Description Relationship Accession
Glucose-dependent insulinotropic receptor SINGLE PROTEIN Q8TDV5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000147262
Ensembl ENSG00000147262
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0043235 (receptor complex)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0008289 (lipid binding)
GO:0031210 (phosphatidylcholine binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0030073 (insulin secretion)
Wikipedia GPR119

Target Cross References - Protein

canSAR Q8TDV5
Human Protein Atlas ENSG00000147262
Guide to Pharmacology 126
Open Targets ENSG00000147262
PharmGKB PA134928131
Pharos Q8TDV5 (Tchem)
Reactome R-HSA-381771 (Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1).)
R-HSA-400511 (Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP).)
UniProt Q495H7 Q4VBN3 Q8TDV5

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR017452 (GPCR_Rhodpsn_7TM.)
IPR028336 (GPR119.)
Pfam PF00001 (7tm_1)
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