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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5573
Target Type SINGLE PROTEIN
Preferred Name Intestinal alkaline phosphatase
Synonyms Object
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Intestinal-type alkaline phosphatase SINGLE PROTEIN P09923

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000163295
Ensembl ENSG00000163295
GO Cellular Component GO:0031225 (anchored component of membrane)
GO:0016021 (integral component of membrane)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0000287 (magnesium ion binding)
GO:0002020 (protease binding)
GO:0004035 (alkaline phosphatase activity)
GO:0008270 (zinc ion binding)
GO Biological Process GO:0016311 (dephosphorylation)
Wikipedia ALPI

Target Cross References - Protein

canSAR P09923
Human Protein Atlas ENSG00000163295
IntAct P09923
PharmGKB PA24728
UniProt B2R7Y4 Q9UBV5 Q53S80 P09923 Q9UCL2

Target Cross References - Domain

InterPro IPR018299 (Alkaline_phosphatase_AS.)
IPR001952 (Alkaline_phosphatase.)
IPR017850 (Alkaline_phosphatase_core.)
IPR017849 (Alkaline_Pase-like_a/b/a.)
Pfam PF00245 (Alk_phosphatase)
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