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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5524
Target Type SINGLE PROTEIN
Preferred Name Protein-arginine N-methyltransferase 1
Synonyms HMT2 | HRMT1L2 | Histone-arginine N-methyltransferase PRMT1 | IR1B4 | Interferon receptor 1-bound protein 4 | PRMT1 | Protein arginine N-methyltransferase 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • epigenetic regulator > writer > protein methyltransferase > protein arginine methyltransferase

Target Components

Component Description Relationship Accession
Protein arginine N-methyltransferase 1 SINGLE PROTEIN Q99873

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000126457
Ensembl ENSG00000126457
GO Cellular Component GO:0005634 (nucleus)
GO:0005829 (cytosol)
GO Molecular Function GO:0005515 (protein binding)
GO:0044020 (histone methyltransferase activity (H4-R3 specific))
GO Biological Process GO:0007166 (cell surface receptor linked signaling pathway)
GO:0031175 (neuron projection development)
Wikipedia PRMT1

Target Cross References - Protein

canSAR Q99873
Human Protein Atlas ENSG00000126457
IntAct Q99873
Guide to Pharmacology 1252 (protein arginine methyltransferase 1)
PharmGKB PA29461
UniProt Q15529 Q2VP93 Q6LEU5 Q99872 Q99873 Q99874 Q9NZ04 Q9NZ05 Q9NZ06

Target Cross References - Domain

InterPro IPR010456 (Ribosomal-L11_MeTrfase_PrmA.)
Pfam PF06325 (PrmA)
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