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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5320
Target Type SINGLE PROTEIN
Preferred Name Myotonin-protein kinase
Synonyms DM-kinase | DM1 protein kinase | DM1PK | DMK | DMPK | DMPK | MDPK | MT-PK | Myotonic dystrophy protein kinase | Myotonin-protein kinase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > agc protein kinase group > agc protein kinase dmpk family > agc protein kinase gek subfamily

Target Components

Component Description Relationship Accession
Myotonin-protein kinase SINGLE PROTEIN Q09013

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000104936
Ensembl ENSG00000104936
GO Molecular Function GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0008016 (regulation of heart contraction)
Wikipedia Myotonin-protein_kinase

Target Cross References - Protein

CGD Myotonic dystrophy 1
Human Protein Atlas ENSG00000104936
IntAct Q09013
Guide to Pharmacology 1505 (dystrophia myotonica-protein kinase)
PharmGKB PA27380
UniProt Q09013 Q16205 Q6P5Z6

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_cat_dom.)
IPR000961 (AGC-kinase_C.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR008271 (Ser/Thr_prot_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR014930 (Myotonic_dystrophy_kinase_coil.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
Pfam PF00069 (Pkinase)
PF08826 (DMPK_coil)

Target Cross References - Structure

PDBe 1WT6 2VD5
CREDO 1WT6 2VD5
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