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Target Report Card

Target Name and Classification

Target ID CHEMBL5261
Preferred Name Serine/threonine-protein kinase TAO1
Synonyms KIAA1361 | Kinase from chicken homolog B | MAP3K16 | MARK Kinase | MARKK | MARKK | PSK-2 | PSK2 | Prostate-derived STE20-like kinase 2 | Prostate-derived sterile 20-like kinase 2 | Serine/threonine-protein kinase TAO1 | TAOK1 | TAOK1 | Thousand and one amino acid protein kinase 1 | hKFC-B | hTAOK1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > ste protein kinase group > ste protein kinase ste20 family > ste protein kinase tao subfamily

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase TAO1 SINGLE PROTEIN Q7L7X3

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000160551
Ensembl ENSG00000160551
GO Cellular Component GO:0005829 (cytosol)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO Biological Process GO:0000236 (mitotic prometaphase)
GO:0006468 (protein phosphorylation)
Wikipedia TAOK1

Target Cross References - Protein

canSAR Q7L7X3
Human Protein Atlas ENSG00000160551
IntAct Q7L7X3
Guide to Pharmacology 2233 (TAO kinase 1)
PharmGKB PA134872946
Reactome REACT_152 (Cell Cycle, Mitotic.)
REACT_383 (DNA Replication.)
UniProt A2RUT8 Q7L7X3 Q96L75 Q9H2K7 Q9H7S5 Q9P2I6

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_cat_dom.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR008271 (Ser/Thr_prot_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
Pfam PF00069 (Pkinase)