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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5048
Target Type SINGLE PROTEIN
Preferred Name Neutral cholesterol ester hydrolase 1
Synonyms AADACL1 | Arylacetamide deacetylase-like 1 | KIAA1363 | NCEH | NCEH1 | Neutral cholesterol ester hydrolase 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Neutral cholesterol ester hydrolase 1 SINGLE PROTEIN Q6PIU2

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000144959
Ensembl ENSG00000144959
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005792 (microsome)
GO:0016021 (integral to membrane)
GO Molecular Function GO:0004091 (carboxylesterase activity)
GO Biological Process GO:0016042 (lipid catabolic process)
Wikipedia NCEH1

Target Cross References - Protein

canSAR Q6PIU2
Human Protein Atlas ENSG00000144959
PharmGKB PA165697847
UniProt B7Z2K4 B7Z3A1 B7Z5U2 B7Z906 B7ZAW6 Q6PIU2 Q86WZ1 Q9P2I4

Target Cross References - Domain

InterPro IPR002168 (Lipase_GDXG_AS.)
IPR013094 (AB_hydrolase_3.)
IPR017157 (Arylacetamide_deacetylase.)
Pfam PF07859 (Abhydrolase_3)
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