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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5038
Target Type SINGLE PROTEIN
Preferred Name Melanin-concentrating hormone receptor 2
Synonyms G-protein coupled receptor 145 | GPR145 | GPRv17 | MCH receptor 2 | MCH-2R | MCH-R2 | MCH2 | MCH2R | MCHR-2 | MCHR2 | Melanin-concentrating hormone receptor 2 | SLT
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > mch receptor

Target Components

Component Description Relationship Accession
Melanin-concentrating hormone receptor 2 SINGLE PROTEIN Q969V1

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111437 Melanin-concentrating hormone receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000152034
Ensembl ENSG00000152034
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0001631 (cysteinyl leukotriene receptor activity)
GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0008528 (G-protein coupled peptide receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007200 (phospholipase C-activating G-protein coupled receptor signaling pathway)
GO:0007218 (neuropeptide signaling pathway)
GO:0061737 (leukotriene signaling pathway)
Wikipedia Melanin-concentrating_hormone_receptor_2

Target Cross References - Protein

canSAR Q969V1
Human Protein Atlas ENSG00000152034
Guide to Pharmacology 281
Open Targets ENSG00000152034
PharmGKB PA134950856
Pharos Q969V1 (Tchem)
Reactome R-HSA-375276 (Peptide ligand-binding receptors.)
R-HSA-416476 (G alpha (q) signalling events.)
R-HSA-418594 (G alpha (i) signalling events.)
UniProt B3KVW4 E1P5D7 Q5VTV7 Q6Q377 Q969V1 Q9BXA8

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR008361 (MCH_rcpt.)
IPR008362 (MCH2_receptor.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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