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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5010
Target Type SINGLE PROTEIN
Preferred Name Monoacylglycerol lipase ABHD6
Synonyms 2-arachidonoylglycerol hydrolase | Abhd6 | Abhydrolase domain-containing protein 6 | Monoacylglycerol lipase ABHD6
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Monoacylglycerol lipase ABHD6 SINGLE PROTEIN Q8R2Y0

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSMUSG00000025277
Ensembl ENSMUSG00000025277
GO Cellular Component GO:0005739 (mitochondrion)
GO:0032281 (AMPA glutamate receptor complex)
GO:0070062 (extracellular exosome)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0047372 (acylglycerol lipase activity)
GO:0004620 (phospholipase activity)
GO Biological Process GO:0009395 (phospholipid catabolic process)
GO:0060292 (long term synaptic depression)
GO:0046464 (acylglycerol catabolic process)
GO:0030336 (negative regulation of cell migration)
GO:0046889 (positive regulation of lipid biosynthetic process)
GO:2000124 (regulation of endocannabinoid signaling pathway)

Target Cross References - Protein

canSAR Q8R2Y0
IntAct Q8R2Y0
UniProt Q9DCD4 Q3TGD2 Q8R2Y0

Target Cross References - Domain

InterPro IPR000639 (Epox_hydrolase-like.)
IPR000073 (AB_hydrolase_1.)
IPR029058 (AB_hydrolase.)
Pfam PF12697 (Abhydrolase_6)
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