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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4903
Target Type SINGLE PROTEIN
Preferred Name Low molecular weight phosphotyrosine protein phosphatase
Synonyms ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | Low molecular weight cytosolic acid phosphatase | Low molecular weight phosphotyrosine protein phosphatase | Red cell acid phosphatase 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > phosphatase > protein phosphatase > tyrosine protein phosphatase

Target Components

Component Description Relationship Accession
Low molecular weight phosphotyrosine protein phosphatase SINGLE PROTEIN P24666

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000143727
Ensembl ENSG00000143727
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0009898 (cytoplasmic side of plasma membrane)
GO:0042383 (sarcolemma)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0003993 (acid phosphatase activity)
GO:0004721 (phosphoprotein phosphatase activity)
GO:0004725 (protein tyrosine phosphatase activity)
GO:0004726 (non-membrane spanning protein tyrosine phosphatase activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0016791 (phosphatase activity)
GO Biological Process GO:0006470 (protein dephosphorylation)
GO:0035335 (peptidyl-tyrosine dephosphorylation)
Wikipedia ACP1

Target Cross References - Protein

canSAR P24666
Human Protein Atlas ENSG00000143727
IntAct P24666
Open Targets ENSG00000143727
PharmGKB PA24446
UniProt A8K1L9 B5MCC7 P24666 P24667 Q16035 Q16036 Q16725 Q3KQX8 Q53RU0

Target Cross References - Domain

InterPro IPR002115 (Tyr_Pase_low_mol_wt_mml.)
IPR017867 (Tyr_phospatase_low_mol_wt.)
IPR023485 (Ptyr_pPase.)
IPR036196 (Ptyr_pPase_sf.)
Pfam PF01451 (LMWPc)

Target Cross References - Structure

PDBe 1XWW 3N8I 4Z99 4Z9A 4Z9B 5JNR 5JNS 5JNT 5KQG 5KQL 5KQM 5KQP 5PNT
CREDO 1XWW 3N8I 4Z99 4Z9A 4Z9B 5JNR 5JNS 5JNT 5KQG 5KQL 5KQM 5KQP 5PNT
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