ChEMBL logo


ChEMBL Statistics
  Loading Statistics...

Target Report Card

Target Name and Classification

Target ID CHEMBL4872
Preferred Name Voltage-gated potassium channel beta subunit Mink
Synonyms Delayed rectifier potassium channel subunit IsK | IKs producing slow voltage-gated potassium channel subunit beta Mink | KCNE1 | Minimal potassium channel | Potassium voltage-gated channel subfamily E member 1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • auxiliary transport protein > slow voltage-gated potassium channel accessory protein family

Target Components

Component Description Relationship Accession
Potassium voltage-gated channel subfamily E member 1 SINGLE PROTEIN P15382

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2221347 Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000180509
Ensembl ENSG00000180509
GO Cellular Component GO:0005764 (lysosome)
GO Molecular Function GO:0005251 (delayed rectifier potassium channel activity)
GO:0015459 (potassium channel regulator activity)
GO Biological Process GO:0006936 (muscle contraction)
GO:0007605 (sensory perception of sound)
GO:0008015 (blood circulation)
GO:0051899 (membrane depolarization)
Wikipedia KCNE1

Target Cross References - Protein

canSAR P15382
CGD Long QT syndrome 5; Jervell and Lange-Nielsen syndrome 2
Human Protein Atlas ENSG00000180509
PharmGKB PA211
UniProt A5H1P2 P15382 Q8N709 Q91Z94

Target Cross References - Domain

InterPro IPR000369 (K_chnl_volt-dep_bsu_KCNE.)
IPR005424 (K_chnl_volt-dep_bsu_KCNE1.)
Pfam PF02060 (ISK_Channel)