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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4851
Target Type SINGLE PROTEIN
Preferred Name Serine/threonine-protein kinase 38-like
Synonyms KIAA0965 | NDR2 protein kinase | NDR2 | Nuclear Dbf2-related kinase 2 | STK38L | Serine/threonine-protein kinase 38-like
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > agc protein kinase group > agc protein kinase ndr family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase 38-like SINGLE PROTEIN Q9Y2H1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000211455
Ensembl ENSG00000211455
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005856 (cytoskeleton)
GO:0015629 (actin cytoskeleton)
GO:0016020 (membrane)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0000287 (magnesium ion binding)
GO:0003779 (actin binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0035556 (intracellular signal transduction)
GO:0051128 (regulation of cellular component organization)
Wikipedia STK38L

Target Cross References - Protein

canSAR Q9Y2H1
Human Protein Atlas ENSG00000211455
IntAct Q9Y2H1
Guide to Pharmacology 1518
Open Targets ENSG00000211455
PharmGKB PA38252
Pharos Q9Y2H1 (Tchem)
UniProt A8K4U0 B4E3J8 Q8TBX7 Q9Y2H1

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR000961 (AGC-kinase_C.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017892 (Pkinase_C.)
Pfam PF00069 (Pkinase)
PF00433 (Pkinase_C)
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