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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4746
Target Type SINGLE PROTEIN
Preferred Name FK506 binding protein 3
Synonyms 25 kDa FK506-binding protein | 25 kDa FKBP | FK506-binding protein 3 | FKBP-25 | FKBP-3 | FKBP25 | FKBP3 | Immunophilin FKBP25 | PPIase FKBP3 | Peptidyl-prolyl cis-trans isomerase FKBP3 | Rapamycin-selective 25 kDa immunophilin | Rotamase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Peptidyl-prolyl cis-trans isomerase FKBP3 SINGLE PROTEIN Q00688

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000100442
Ensembl ENSG00000100442
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0003723 (RNA binding)
GO:0003755 (peptidyl-prolyl cis-trans isomerase activity)
GO:0005515 (protein binding)
GO:0005528 (FK506 binding)
GO:0016853 (isomerase activity)
GO:0038023 (signaling receptor activity)
GO Biological Process GO:0000413 (protein peptidyl-prolyl isomerization)
GO:0007165 (signal transduction)
GO:0061077 (chaperone-mediated protein folding)
Wikipedia FKBP3

Target Cross References - Protein

canSAR Q00688
Human Protein Atlas ENSG00000100442
IntAct Q00688
Open Targets ENSG00000100442
PharmGKB PA28160
UniProt B2R4Q9 Q00688 Q14317

Target Cross References - Domain

InterPro IPR001179 (PPIase_FKBP_dom.)
IPR023566 (PPIase_FKBP.)
Pfam PF00254 (FKBP_C)

Target Cross References - Structure

PDBe 1PBK 5D75 5GPG
CREDO 1PBK 5D75 5GPG
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