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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4707
Target Type SINGLE PROTEIN
Preferred Name Matrix metalloproteinase 26
Synonyms Endometase | MMP-26 | MMP26 | Matrilysin-2 | Matrix metalloproteinase-26
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mam clan > metallo protease m10a subfamily

Target Components

Component Description Relationship Accession
Matrix metalloproteinase-26 SINGLE PROTEIN Q9NRE1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000167346
Ensembl ENSG00000167346
GO Cellular Component GO:0005576 (extracellular region)
GO:0005578 (proteinaceous extracellular matrix)
GO:0031012 (extracellular matrix)
GO Molecular Function GO:0004222 (metalloendopeptidase activity)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0030574 (collagen catabolic process)
GO:0050728 (negative regulation of inflammatory response)
Wikipedia MMP26

Target Cross References - Protein

canSAR Q9NRE1
Human Protein Atlas ENSG00000167346
Guide to Pharmacology 1648
Open Targets ENSG00000167346
PharmGKB PA30883
UniProt Q3MJ78 Q9GZS2 Q9NR87 Q9NRE1

Target Cross References - Domain

InterPro IPR001818 (Pept_M10_metallopeptidase.)
IPR006026 (Peptidase_Metallo.)
IPR021190 (Pept_M10A.)
IPR024079 (MetalloPept_cat_dom.)
IPR028736 (MMP26.)
IPR033739 (M10A_MMP.)
Pfam PF00413 (Peptidase_M10)
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