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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4633
Target Type SINGLE PROTEIN
Preferred Name Voltage-gated potassium channel subunit Kv1.3
Synonyms HGK5 | HGK5 | HLK3 | HPCN3 | KCNA3 | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated K(+) channel HuKIII | Voltage-gated potassium channel subunit Kv1.3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > potassium channels > voltage-gated potassium channel

Target Components

Component Description Relationship Accession
Potassium voltage-gated channel subfamily A member 3 SINGLE PROTEIN P22001

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2362996 Voltage-gated potassium channel PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000177272
Ensembl ENSG00000177272
GO Cellular Component GO:0008076 (voltage-gated potassium channel complex)
GO Molecular Function GO:0005251 (delayed rectifier potassium channel activity)
Wikipedia KCNA3

Target Cross References - Protein

canSAR P22001
Human Protein Atlas ENSG00000177272
Guide to Pharmacology 540 (Kv1.3)
PharmGKB PA30021
UniProt P22001 Q5VWN2

Target Cross References - Domain

InterPro IPR000210 (BTB/POZ-like.)
IPR003091 (K_chnl.)
IPR003131 (K_chnl_volt-dep_Kv_tetra.)
IPR003968 (K_chnl_volt-dep_Kv.)
IPR003972 (K_chnl_volt-dep_Kv1.)
IPR004050 (K_chnl_volt-dep_Kv1.3.)
IPR005821 (Ion_trans.)
IPR011333 (BTB/POZ_fold.)
Pfam PF00520 (Ion_trans)
PF02214 (K_tetra)
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