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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4589
Target Type SINGLE PROTEIN
Preferred Name Glutathione S-transferase Mu 2
Synonyms GST class-mu 2 | GST4 | GSTM2 | GSTM2-2 | Glutathione S-transferase Mu 2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Glutathione S-transferase Mu 2 SINGLE PROTEIN P28161

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000213366
Ensembl ENSG00000213366
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004364 (glutathione transferase activity)
GO Biological Process GO:0006749 (glutathione metabolic process)
GO:0042178 (xenobiotic catabolic process)
Wikipedia GSTM2

Target Cross References - Protein

canSAR P28161
Human Protein Atlas ENSG00000213366
PharmGKB PA29023
UniProt P28161 Q2M318 Q5TZY5 Q8WWE1

Target Cross References - Domain

InterPro IPR003081 (GST_mu.)
IPR004045 (Glutathione_S-Trfase_N.)
IPR004046 (GST_C.)
IPR010987 (Glutathione-S-Trfase_C-like.)
IPR012335 (Thioredoxin_fold.)
IPR012336 (Thioredoxin-like_fold.)
IPR017933 (Glutathione_S_Trfase/Cl_chnl_C.)
Pfam PF00043 (GST_C)
PF02798 (GST_N)

Target Cross References - Structure

PDBe 1HNA 1HNB 1HNC 1XW5 1YKC 2AB6 2C4J 2GTU 3GTU 3GUR
CREDO 1HNA 1HNB 1HNC 1XW5 1YKC 2AB6 2C4J 2GTU 3GTU 3GUR
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