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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4520
Target Type SINGLE PROTEIN
Preferred Name Dipeptidyl peptidase III
Synonyms DPP III | DPP3 | Dipeptidyl aminopeptidase III | Dipeptidyl arylamidase III | Dipeptidyl peptidase 3 | Dipeptidyl peptidase III | Enkephalinase B
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m49 family

Target Components

Component Description Relationship Accession
Dipeptidyl peptidase 3 SINGLE PROTEIN Q9NY33

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000254986
Ensembl ENSG00000254986
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO:0016607 (nuclear speck)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0005515 (protein binding)
GO:0008233 (peptidase activity)
GO:0008237 (metallopeptidase activity)
GO:0008239 (dipeptidyl-peptidase activity)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006508 (proteolysis)
Wikipedia DPP3

Target Cross References - Protein

canSAR Q9NY33
Human Protein Atlas ENSG00000254986
IntAct Q9NY33
Open Targets ENSG00000254986
PharmGKB PA27466
UniProt B2RDB5 B4DLX4 F5H8L6 O95748 Q969H2 Q9BV67 Q9HAL6 Q9NY33

Target Cross References - Domain

InterPro IPR005317 (Dipeptidyl-peptase3.)

Target Cross References - Structure

PDBe 3FVY 3T6B 3T6J 5E2Q 5E33 5E3A 5E3C 5EGY 5EHH
CREDO 3FVY 3T6B 3T6J 5E2Q 5E33 5E3A 5E3C 5EGY 5EHH
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