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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4502
Target Type SINGLE PROTEIN
Preferred Name Cytidine deaminase
Synonyms CDA | CDD | Cytidine aminohydrolase | Cytidine deaminase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Cytidine deaminase SINGLE PROTEIN P32320

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000158825
Ensembl ENSG00000158825
GO Cellular Component GO:0005576 (extracellular region)
GO:0005829 (cytosol)
GO Molecular Function GO:0001882 (nucleoside binding)
GO:0003824 (catalytic activity)
GO:0004126 (cytidine deaminase activity)
GO:0005515 (protein binding)
GO:0008270 (zinc ion binding)
GO:0016787 (hydrolase activity)
GO:0042802 (identical protein binding)
GO:0042803 (protein homodimerization activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0007166 (cell surface receptor signaling pathway)
GO:0008655 (pyrimidine-containing compound salvage)
GO:0009972 (cytidine deamination)
GO:0019858 (cytosine metabolic process)
GO:0030308 (negative regulation of cell growth)
GO:0043097 (pyrimidine nucleoside salvage)
GO:0045980 (negative regulation of nucleotide metabolic process)
GO:0051289 (protein homotetramerization)
Wikipedia Cytidine_deaminase

Target Cross References - Protein

canSAR P32320
Human Protein Atlas ENSG00000158825
IntAct P32320
Open Targets ENSG00000158825
PharmGKB PA98
Reactome R-HSA-73614 (Pyrimidine salvage reactions.)
UniProt P32320

Target Cross References - Domain

InterPro IPR002125 (CMP_dCMP_Zn-bd.)
IPR006262 (Cyt_deam_tetra.)
IPR016192 (APOBEC/CMP_deaminase_Zn-bd.)
IPR016193 (Cytidine_deaminase-like.)
Pfam PF00383 (dCMP_cyt_deam_1)

Target Cross References - Structure

PDBe 1MQ0
CREDO 1MQ0
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