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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4491
Target Type SINGLE PROTEIN
Preferred Name Glutathione S-transferase kappa 1
Synonyms GST 13-13 | GST class-kappa | GSTK1 | GSTK1-1 | Glutathione S-transferase kappa 1 | Glutathione S-transferase subunit 13 | hGSTK1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Glutathione S-transferase kappa 1 SINGLE PROTEIN Q9Y2Q3

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000197448
Ensembl ENSG00000197448
GO Cellular Component GO:0005622 (intracellular)
GO:0005739 (mitochondrion)
GO:0005743 (mitochondrial inner membrane)
GO:0005759 (mitochondrial matrix)
GO:0005777 (peroxisome)
GO:0016020 (membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004364 (glutathione transferase activity)
GO:0004602 (glutathione peroxidase activity)
GO:0005102 (receptor binding)
GO:0005515 (protein binding)
GO:0015035 (protein disulfide oxidoreductase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006749 (glutathione metabolic process)
GO:0030855 (epithelial cell differentiation)
GO:0055114 (oxidation-reduction process)
GO:0098869 (cellular oxidant detoxification)
GO:1901687 (glutathione derivative biosynthetic process)
Wikipedia GSTK1

Target Cross References - Protein

canSAR Q9Y2Q3
Human Protein Atlas ENSG00000197448
IntAct Q9Y2Q3
Open Targets ENSG00000197448
PharmGKB PA134948237
Reactome R-HSA-156590 (Glutathione conjugation.)
UniProt B4DIH1 B4DSY2 Q6P4H0 Q7Z520 Q9P1S4 Q9Y2Q3

Target Cross References - Domain

InterPro IPR001853 (DSBA-like_thioredoxin_dom.)
IPR012336 (Thioredoxin-like_fold.)
IPR014440 (HCCAis_GSTk.)
Pfam PF01323 (DSBA)

Target Cross References - Structure

PDBe 1YZX 3RPN 3RPP
CREDO 1YZX 3RPN 3RPP
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