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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4443
Target Type SINGLE PROTEIN
Preferred Name Fucosyltransferase 6
Synonyms Alpha-(1,3)-fucosyltransferase 6 | FCT3A | FUT6 | Fuc-TVI | FucT-VI | Fucosyltransferase 6 | Fucosyltransferase VI | Galactoside 3-L-fucosyltransferase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Alpha-(1,3)-fucosyltransferase 6 SINGLE PROTEIN P51993

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000156413
Ensembl ENSG00000156413
GO Cellular Component GO:0000139 (Golgi membrane)
GO:0005794 (Golgi apparatus)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0032580 (Golgi cisterna membrane)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0008417 (fucosyltransferase activity)
GO:0016740 (transferase activity)
GO:0016757 (transferase activity, transferring glycosyl groups)
GO:0017060 (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity)
GO:0046920 (alpha-(1->3)-fucosyltransferase activity)
GO Biological Process GO:0006486 (protein glycosylation)
GO:0006487 (protein N-linked glycosylation)
GO:0036065 (fucosylation)
GO:0042355 (L-fucose catabolic process)
Wikipedia FUT6

Target Cross References - Protein

canSAR P51993
CGD Fucosyltransferase 6 deficiency
Human Protein Atlas ENSG00000156413
Open Targets ENSG00000156413
PharmGKB PA28433
UniProt A6NEX0 D6W637 P51993 Q9UND8

Target Cross References - Domain

InterPro IPR001503 (Glyco_trans_10.)
IPR031481 (Glyco_tran_10_N.)
Pfam PF00852 (Glyco_transf_10)
PF17039 (Glyco_tran_10_N)
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