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Target Report Card

Target Name and Classification

Target ID CHEMBL4423
Preferred Name C-C chemokine receptor type 6
Synonyms C-C CKR-6 | C-C chemokine receptor type 6 | CC-CKR-6 | CCR-6 | CCR6 | CD_antigen=CD196 | CKR-L3 | CKRL3 | CMKBR6 | Chemokine receptor-like 3 | DRY6 | G-protein coupled receptor 29 | GPR-CY4 | GPR29 | GPRCY4 | LARC receptor | STRL22
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > chemokine receptor > cc chemokine receptor

Target Components

Component Description Relationship Accession
C-C chemokine receptor type 6 SINGLE PROTEIN P51684

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000112486
Ensembl ENSG00000112486
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0016493 (C-C chemokine receptor activity)
GO Biological Process GO:0002407 (dendritic cell chemotaxis)
GO:0006959 (humoral immune response)
GO:0006968 (cellular defense response)
GO:0007204 (elevation of cytosolic calcium ion concentration)
Wikipedia C-C_chemokine_receptor_type_6

Target Cross References - Protein

canSAR P51684
Human Protein Atlas ENSG00000112486
Guide to Pharmacology 63 (CCR6)
PharmGKB PA26171
Reactome REACT_14797 (Signaling by GPCR.)
UniProt E1P5C6 P51684 P78553 Q92846

Target Cross References - Domain

InterPro IPR000276 (7TM_GPCR_Rhodpsn.)
IPR000355 (Chemokine_rcpt.)
IPR004067 (Chemokine_CCR6.)
IPR017452 (GPCR_Rhodpsn_supfam.)
Pfam PF00001 (7tm_1)