ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL4370
Target Type SINGLE PROTEIN
Preferred Name UDP-glucuronosyltransferase 2B7
Synonyms 3,4-catechol estrogen-specific UDPGT | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
UDP-glucuronosyltransferase 2B7 SINGLE PROTEIN P16662

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000171234
Ensembl ENSG00000171234
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031090 (organelle membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0001972 (retinoic acid binding)
GO:0015020 (glucuronosyltransferase activity)
GO:0016740 (transferase activity)
GO:0016757 (transferase activity, transferring glycosyl groups)
GO:0016758 (transferase activity, transferring hexosyl groups)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0008152 (metabolic process)
GO:0008202 (steroid metabolic process)
GO:0008209 (androgen metabolic process)
GO:0009813 (flavonoid biosynthetic process)
GO:0052695 (cellular glucuronidation)
GO:0052696 (flavonoid glucuronidation)
Wikipedia UGT2B7

Target Cross References - Protein

canSAR P16662
Human Protein Atlas ENSG00000171234
IntAct P16662
Open Targets ENSG00000171234
PharmGKB PA361
Reactome R-HSA-156588 (Glucuronidation.)
UniProt B2R810 P16662 Q6GTW0

Target Cross References - Domain

InterPro IPR002213 (UDP_glucos_trans.)
Pfam PF00201 (UDPGT)

Target Cross References - Structure

PDBe 2O6L
CREDO 2O6L
spacer
spacer