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Target Report Card

Target Name and Classification

Target ID CHEMBL4327
Preferred Name Fatty acid transport protein 4
Synonyms ACSVL4 | FATP-4 | FATP4 | Fatty acid transport protein 4 | Long-chain fatty acid transport protein 4 | SLC27A4 | Solute carrier family 27 member 4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc27 family of fatty acid transporters

Target Components

Component Description Relationship Accession
Long-chain fatty acid transport protein 4 SINGLE PROTEIN Q6P1M0

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000167114
Ensembl ENSG00000167114
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0005886 (plasma membrane)
GO:0005902 (microvillus)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031526 (brush border membrane)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003824 (catalytic activity)
GO:0004467 (long-chain fatty acid-CoA ligase activity)
GO:0015245 (fatty acid transporter activity)
GO:0016874 (ligase activity)
GO:0031957 (very long-chain fatty acid-CoA ligase activity)
GO Biological Process GO:0000038 (very long-chain fatty acid metabolic process)
GO:0001579 (medium-chain fatty acid transport)
GO:0001676 (long-chain fatty acid metabolic process)
GO:0006629 (lipid metabolic process)
GO:0006631 (fatty acid metabolic process)
GO:0006869 (lipid transport)
GO:0007584 (response to nutrient)
GO:0008152 (metabolic process)
GO:0015908 (fatty acid transport)
GO:0015909 (long-chain fatty acid transport)
GO:0042760 (very long-chain fatty acid catabolic process)
GO:0043588 (skin development)
GO:0044539 (long-chain fatty acid import)
Wikipedia SLC27A4

Target Cross References - Protein

canSAR Q6P1M0
CGD Ichthyosis prematurity syndrome
Human Protein Atlas ENSG00000167114
IntAct Q6P1M0
Guide to Pharmacology 1111
Open Targets ENSG00000167114
PharmGKB PA35872
Reactome R-HSA-5619108 (Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS).)
R-HSA-804914 (Transport of fatty acids.)
UniProt A8K2F7 O95186 Q6P1M0 Q96G53

Target Cross References - Domain

InterPro IPR000873 (AMP-dep_Synth/Lig.)
IPR020845 (AMP-binding_CS.)
IPR022272 (Lipocalin_CS.)
IPR025110 (AMP-bd_C.)
IPR030304 (FATP4.)
Pfam PF00501 (AMP-binding)
PF13193 (AMP-binding_C)