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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4323
Target Type SINGLE PROTEIN
Preferred Name Phospholipase A2 group V
Synonyms Calcium-dependent phospholipase A2 | Group V phospholipase A2 | PLA2-10 | PLA2G5 | Phosphatidylcholine 2-acylhydrolase 5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Calcium-dependent phospholipase A2 SINGLE PROTEIN P39877

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000127472
Ensembl ENSG00000127472
GO Cellular Component GO:0005576 (extracellular region)
GO Molecular Function GO:0005509 (calcium ion binding)
GO:0047498 (calcium-dependent phospholipase A2 activity)
GO Biological Process GO:0016042 (lipid catabolic process)
Wikipedia PLA2G5

Target Cross References - Protein

canSAR P39877
CGD Fleck retina, familial benign
Human Protein Atlas ENSG00000127472
Guide to Pharmacology 1430 (PLA2-G5)
PharmGKB PA33366
UniProt P39877 Q8N435

Target Cross References - Domain

InterPro IPR001211 (Phospholipase_A2_euk.)
IPR013090 (Phospholipase_A2_AS.)
IPR016090 (Phospholipase_A2.)
Pfam PF00068 (Phospholip_A2_1)
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